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The creation of a single organelle from two or more organelles. The directed movement of substances in synaptic membrane-bounded vesicles within the neuron along the cytoskeleton either toward or away from the neuronal cell body. A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process whereby most molecules are secreted from eukaryotic cells. Fusion of the membrane of a transport vesicle with its target membrane. Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft. The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane. The cellular process that joins two lipid bilayers to form a single membrane. Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane. Fusion of the membrane of a synaptic vesicle with its target presynaptic membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft. The directed movement of substances into, out of or within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane. Vesicles are then targeted to, and fuse with, an acceptor membrane.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: synaptic vesicle fusion to presynaptic membrane
Acc: GO:0031629
Aspect: Biological Process
Desc: Fusion of the membrane of a synaptic vesicle with its target presynaptic membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.
Synonyms:
  • synaptic vesicle internalization
  • synaptic vesicle fusion
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 7 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031629 - synaptic vesicle fusion to presynaptic membrane (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle