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Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin. The assembly of chromatin into heterochromatin, a compact and highly condensed form that is often, but not always, transcriptionally silent. The assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. Any process that reduces the extent of heterochromatin formation; reduces the size of a chromosomal region converted to heterochromatin. Any process the modulates the frequency, rate or extent of chromatin assembly. Chromatin assembly is the assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. Any process that modulates the frequency, rate, extent or location of heterochromatin formation. Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. Any process that modulates the frequency, rate or extent of chromatin assembly or disassembly. Any process that stops, prevents or reduces the frequency, rate or extent of heterochromatin formation. The formation or destruction of chromatin structures. Any process that stops, prevents or reduces the frequency, rate or extent of chromatin assembly or disassembly.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of heterochromatin formation
Acc: GO:0031452
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of heterochromatin formation.
Synonyms:
  • down regulation of heterochromatin formation
  • down-regulation of heterochromatin formation
  • downregulation of heterochromatin formation
  • inhibition of heterochromatin formation
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031452 - negative regulation of heterochromatin formation (interactive image map)
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