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Any process that modulates the frequency, rate or extent of cellular component biogenesis, the process by which a cellular component is synthesized, aggregates, and bonds together. Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins. The cellular process by which a protein complex is synthesized, aggregates, and bonds together. Includes the synthesis of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex. The aggregation, arrangement and bonding together of a set of macromolecules to form a complex. Any process that stops, prevents or reduces the frequency, rate, or extent of integrin activation. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that stops, prevents or reduces the rate or extent of exocyst assembly. Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. Any process that decreases the rate, frequency or extent of a process involved in starting transcription from the RNA polymerase II promoter. The aggregation, arrangement and bonding together of a set of components to form a protein complex. Any process that stops, prevents or reduces the frequency, rate or extent of protein complex assembly. Any process that stops, prevents or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. Any process that stops, prevents or reduces the frequency, rate or extent of the process of creating protein polymers. Any process that decreases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion. Any process that modulates the frequency, rate or extent of protein complex assembly. Any process that stops, prevents or reduces the frequency, rate or extent of protein oligomerization. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of protein complex assembly
Acc: GO:0031333
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of protein complex assembly.
Synonyms:
  • down regulation of protein complex assembly
  • downregulation of protein complex assembly
  • inhibition of protein complex assembly
  • down-regulation of protein complex assembly
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 81 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031333 - negative regulation of protein complex assembly (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle