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Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1. A protein complex that includes a ubiquitin-protein ligase and other proteins that may confer substrate specificity on the complex. A ubiquitin ligase complex found in the cytoplasm.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: VCB complex
Acc: GO:0030891
Aspect: Cellular Component
Desc: A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1.
Synonyms:
  • pVHL-elongin C-elongin B complex
  • VHL complex
  • von Hippel-Lindau tumor suppressor complex
Proteins in PDR annotated with:
   This term: 12 [Search]
   Term or descendants: 12 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030891 - VCB complex (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle