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Catalysis of the ligation of an acid and a thiol via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the ligation of two substances via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the reaction: ATP + acetoacetate + CoA = AMP + diphosphate + acetoacetyl-CoA.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: acetoacetate-CoA ligase activity
Acc: GO:0030729
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + acetoacetate + CoA = AMP + diphosphate + acetoacetyl-CoA.
Synonyms:
  • acetoacetyl-CoA synthetase activity
  • acetoacetate:CoA ligase (AMP-forming)
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030729 - acetoacetate-CoA ligase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle