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Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+. Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered. Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and NAD+ or NADP+ acts as an electron acceptor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: [methionine synthase] reductase activity
Acc: GO:0030586
Aspect: Molecular Function
Desc: Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+.
Synonyms:
  • methionine synthase reductase activity
  • methionine synthase-cobalamin methyltransferase (cob(II)alamin reducing)
  • methionine synthase-methylcob(I)alamin,S-adenosylhomocysteine:NADP+ oxidoreductase activity
  • methionine synthase cob(II)alamin reductase (methylating) activity
  • [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing) activity
  • 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030586 - [methionine synthase] reductase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle