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The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. The process whereby a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell or any cell of the myeloid leukocyte or lymphocyte lineages. The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. The process whereby a relatively unspecialized monocyte acquires the specialized features of a macrophage. Any process that modulates the frequency, rate or extent of macrophage differentiation. Any process that activates or increases the frequency, rate or extent of macrophage differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of macrophage differentiation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: macrophage differentiation
Acc: GO:0030225
Aspect: Biological Process
Desc: The process whereby a relatively unspecialized monocyte acquires the specialized features of a macrophage.
Synonyms:
  • macrophage cell differentiation
Proteins in PDR annotated with:
   This term: 14 [Search]
   Term or descendants: 29 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030225 - macrophage differentiation (interactive image map)
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