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The adhesion of one platelet to one or more other platelets via adhesion molecules. Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part. The process by which a fluid solution, or part of it, changes into a solid or semisolid mass. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. The series of events that restore integrity to a damaged tissue, following an injury. A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: platelet activation
Acc: GO:0030168
Aspect: Biological Process
Desc: A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
Proteins in PDR annotated with:
   This term: 34 [Search]
   Term or descendants: 56 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030168 - platelet activation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle