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A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP. A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. Mitochondrial complex that possesses isocitrate dehydrogenase (NAD+) activity. Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane. Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity. Any of the heteromeric enzymes that act in the TCA cycle. The volume enclosed by the mitochondrial inner membrane. Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: mitochondrial tricarboxylic acid cycle enzyme complex
Acc: GO:0030062
Aspect: Cellular Component
Desc: Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle.
Synonyms:
  • TCA cycle enzyme complex
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 26 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030062 - mitochondrial tricarboxylic acid cycle enzyme complex (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle