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The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. A large multisubunit complex which catalyzes protein degradation. This complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex. A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex. A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. Any constituent part of a cell, the basic structural and functional unit of all organisms. A multisubunit complex that recognizes and unfolds core proteasome substrate proteins, and translocates them to the core complex in an ATP dependent manner. Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: proteasome accessory complex
Acc: GO:0022624
Aspect: Cellular Component
Desc: A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 156 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0022624 - proteasome accessory complex (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle