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The process by which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils. The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families. The process by which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein. The process by which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. The process by which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex. The process by which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. The process by which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex. Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation. The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis. Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation. Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis. Any process that modulates the frequency, rate, or extent of antigen processing and presentation. The process by which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex. Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor. The process by which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. The process by which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. The process by which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: antigen processing and presentation
Acc: GO:0019882
Aspect: Biological Process
Desc: The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
Synonyms:
  • antigen presentation
  • antigen processing
  • GO:0030333
Proteins in PDR annotated with:
   This term: 269 [Search]
   Term or descendants: 344 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0019882 - antigen processing and presentation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle