YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

The enzymatic addition of prenyl moieties to proteins as a posttranslational modification; geranyl, farnesyl, or geranylgeranyl groups may be added. The enzymatic addition of a geranylgeranyl moiety to a protein as a posttranslational modification. The covalent attachment of a prenyl moiety to a protein amino acid. The covalent attachment of a geranylgeranyl moiety to a protein amino acid. The posttranslational modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: protein amino acid geranylgeranylation
Acc: GO:0018348
Aspect: Biological Process
Desc: The covalent attachment of a geranylgeranyl moiety to a protein amino acid.
Synonyms:
  • C-terminal protein geranylgeranylation
Proteins in PDR annotated with:
   This term: 25 [Search]
   Term or descendants: 25 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0018348 - protein amino acid geranylgeranylation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle