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Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group. Catalysis of the hydrolysis of 3'-phosphotyrosyl moieties formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA. Catalysis of the hydrolysis of phosphotyrosyl moieties formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 3'-tyrosyl-DNA phosphodiesterase activity
Acc: GO:0017005
Aspect: Molecular Function
Desc: Catalysis of the hydrolysis of 3'-phosphotyrosyl moieties formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA.
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0017005 - 3'-tyrosyl-DNA phosphodiesterase activity (interactive image map)
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