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Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein. Catalysis of the removal of terminal peptide residues that are substituted, cyclized or linked by isopeptide bonds (peptide linkages other than those of alpha-carboxyl to alpha-amino groups). Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: pyroglutamyl-peptidase activity
Acc: GO:0016920
Aspect: Molecular Function
Desc: Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein.
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016920 - pyroglutamyl-peptidase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle