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Catalysis of the reaction: creatinine + H2O = N-methylhydantoin + NH3. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2. Catalysis of the reaction: dCTP + 2 H2O = dUMP + diphosphate + NH3. Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds. Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3. Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3. Catalysis of the reaction: cyromazine + H2O = N-cyclopropylammeline + NH3. Catalysis of the reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + H2O = 5-amino-6-(5-phosphoribosylamino)uracil + NH3. Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid. Catalysis of the reaction: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate + H2O = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate + NH3. Catalysis of the reaction: N-cyclopropylammeline + H2O = N-cyclopropylammelide + NH3. Catalysis of the reaction: 4-aminoimidazole + H2O = unidentified product + NH3. Catalysis of the reaction: adenosine + H2O = inosine + NH3. Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = S-inosyl-L-homocysteine + NH3. Catalysis of the reaction: cytidine + H2O = uridine + NH3. Catalysis of the reaction: 2-amino-4-hydroxypteridine + H2O = 2,4-dihydroxypteridine + NH3. Catalysis of the reaction: AMP + H2O = IMP + NH3. Catalysis of the reaction: sepiapterin + H2O = xanthopterin-B2 + NH3. Catalysis of the reaction: ADP + H2O = IDP + NH3. Catalysis of the reaction: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + NH3. Catalysis of the reaction: 5'-AMP + H2O = 5'-IMP + NH3. Catalysis of the reaction: blasticidin S + H2O = deaminohydroxyblasticidin S + NH3. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring. Catalysis of the reaction: H2O + 1-pyrroline-4-hydroxy-2-carboxylate = NH3 + 2,5-dioxopentanoate. Catalysis of the reaction: dCTP + H2O = dUTP + NH3. Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. Catalysis of the reaction: guanine + H2O = xanthine + NH3. Catalysis of the reaction: ATP + H2O = ITP + NH3. Catalysis of the reaction: cytosine + H2O = uracil + NH3. Catalysis of the reaction: guanosine + H2O = xanthosine + NH3. Catalysis of the reaction: dCMP + H2O = dUMP + NH3.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
Acc: GO:0016814
Aspect: Molecular Function
Desc: Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2.
Proteins in PDR annotated with:
   This term: 13 [Search]
   Term or descendants: 301 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016814 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle