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Catalysis of the cleavage of N6-(L-1,3-dicarboxypropyl)-L-lysine to release an amino acid (lysine or glutamate), with the concomitant reduction of an electron acceptor. Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate. Catalysis of the reaction: tauropine + NAD+ + H2O = taurine + pyruvate + NADH. Catalysis of the reaction: N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH. Catalysis of the reaction: NADP+ + L-pipecolate = NADPH + delta(1)-piperideine-2-carboxylate. Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-lysine + NADP+ + H2O = L-lysine + pyruvate + NADPH. Catalysis of the reaction: N-(carboxymethyl)-D-alanine + NAD+ + H2O = glycine + pyruvate + NADH. Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+. Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H+. Catalysis of the reaction: 2,2'-iminodipropanoate + NAD+ + H2O = L-alanine + pyruvate + NADH. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of the reaction: 2 NADP+ + tetra-hydro-biopterin = 2 NADPH + 2 H+ + biopterin. Catalysis of the reactions: hydroxylamine + NH3 = hydrazine + H2O and hydrazine + acceptor = N2 + reduced acceptor. Catalysis of the reaction: 10-formyltetrahydrofolate + NADP+ + H2O = tetrahydrofolate + CO2 + NADPH + H+. Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + H+. Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+. Catalysis of the reaction: queuine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH + 2 H+. Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+. Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+. Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH. Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+. Catalysis of the reaction: NAD(P)+ + thiomorpholine-3-carboxylate = NAD(P)H + 3,4-dehydro-1,4-thiomorpholine-3-carboxylate. Catalysis of the reaction: 1,2-dihydrovomilenine + NADP+ = vomilenine + NADPH + H+. Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+. Catalysis of the reaction: H2O + NADP+ + N5-(L-1-carboxyethyl)-L-ornithine = NADPH + pyruvate + L-ornithine. Catalysis of the reaction: (R)-canadine + 2 NADP+ = berberine + 2 NADPH + H+. Catalysis of the reaction: H2O + NAD+ + (2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate = NADH + pyruvate + L-2-aminopentanoic acid. Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+. Catalysis of the reaction: NADPH + 1,2-dehydroreticulinium = NADP+ + R-reticuline. Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+. Catalysis of the reaction: (-)-ephedrine + NAD+ = (R)-2-methylimino-1-phenylpropan-1-ol + NADH. Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. Catalysis of the reaction: L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+. Catalysis of the reaction: beta-alanopine + NAD+ + H2O = beta-alanine + pyruvate + NADH. Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine. Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
Acc: GO:0016646
Aspect: Molecular Function
Desc: Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP.
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 207 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016646 - oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle