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Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection. Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: PML body
Acc: GO:0016605
Aspect: Cellular Component
Desc: A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.
Synonyms:
  • ND10
  • nuclear dot
  • PML NB
  • PML nuclear body
Proteins in PDR annotated with:
   This term: 64 [Search]
   Term or descendants: 64 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016605 - PML body (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle