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Any transcription regulator activity that prevents or downregulates transcription. Any activity that stops or downregulates transcription of genes globally, and is not specific to a particular gene or gene set. Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. Any activity that stops or downregulates transcription of specific genes or sets of genes. The function of a transcription cofactor that represses transcription from a RNA polymerase II promoter; does not bind DNA itself. Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor. Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: transcription repressor activity
Acc: GO:0016564
Aspect: Molecular Function
Desc: Any transcription regulator activity that prevents or downregulates transcription.
Synonyms:
  • transcriptional repressor activity
  • negative transcriptional regulator activity
Proteins in PDR annotated with:
   This term: 707 [Search]
   Term or descendants: 1040 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016564 - transcription repressor activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle