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Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose. Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides. Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Catalysis of the hydrolysis of any glycosyl bond. Catalysis of the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides. Catalysis of the hydrolysis of any O-glycosyl bond.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: hexosaminidase activity
Acc: GO:0015929
Aspect: Molecular Function
Desc: Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides.
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 58 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0015929 - hexosaminidase activity (interactive image map)
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