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Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks. Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: Type III site-specific deoxyribonuclease activity
Acc: GO:0015668
Aspect: Molecular Function
Desc: Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites.
Synonyms:
  • Type III restriction enzyme activity
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0015668 - Type III site-specific deoxyribonuclease activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle