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Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + azole(in) = H+(in) + azole(out). Azoles are heterocyclic compounds found in many biologically important substances. Enables the directed movement of fluconazole into, out of, within or between cells. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + fluconazole(in) = H+(in) + fluconazole(out). Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, into, out of, within or between cells. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + drug(in) = H+(in) + drug(out).

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: fluconazole:hydrogen antiporter activity
Acc: GO:0015313
Aspect: Molecular Function
Desc: Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + fluconazole(in) = H+(in) + fluconazole(out).
Synonyms:
  • fluconazole:proton antiporter activity
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0015313 - fluconazole:hydrogen antiporter activity (interactive image map)
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