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The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating (alpha1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues. The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization. The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha1->4 linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: heparan sulfate proteoglycan biosynthetic process, enzymatic modification
Acc: GO:0015015
Aspect: Biological Process
Desc: The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization.
Synonyms:
  • heparan sulfate proteoglycan formation, enzymatic modification
  • heparan sulphate proteoglycan biosynthetic process, enzymatic modification
  • heparan sulphate proteoglycan biosynthesis, enzymatic modification
  • heparan sulfate proteoglycan anabolism, enzymatic modification
  • heparan sulfate proteoglycan synthesis, enzymatic modification
  • heparin proteoglycan biosynthetic process, enzymatic modification
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0015015 - heparan sulfate proteoglycan biosynthetic process, enzymatic modification (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle