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The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. A process whereby force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control. Any process that modulates the frequency, rate or extent of striated muscle contraction. Any process that modulates the frequency, rate or extent of skeletal muscle contraction. Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system. Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction
Acc: GO:0014852
Aspect: Biological Process
Desc: Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0014852 - regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction (interactive image map)
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