YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

The hydrolysis of a peptide bond or bonds within a protein as part of protein maturation, the process leading to the attainment of the full functional capacity of a protein. Any process that modulates the rate, frequency or extent of protein maturation by peptide bond cleavage. Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process whereby plasminogen is processed to plasmin. The process whereby inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide. Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process whereby plasminogen is processed to plasmin. Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage. The proteolytic processing of an inactive enzyme to an active form.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of plasminogen activation
Acc: GO:0010757
Aspect: Biological Process
Desc: Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process whereby plasminogen is processed to plasmin.
Synonyms:
  • inhibition of plasminogen activation
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0010757 - negative regulation of plasminogen activation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle