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The regulated release of cytokines from a cell or group of cells. Cytokines are any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. The controlled release of proteins from a cell or group of cells. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. The regulated release of renin into the blood stream by juxtoglomerular cells. Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell or group of cells. The directed movement of proteins into, out of, within or between cells by means of some external agent such as a transporter or pore. The process by which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways. The controlled release of a substance by a cell, a group of cells, or a tissue. The directed movement of a protein to a specific location. The process by which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence. The regulated release of proteins by a platelet or group of platelets. The process by which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway. The controlled release of lysosomal enzymes by a cell or group of cells. Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a protein from a cell or group of cells. The process by which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins. The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells, or within a multicellular organism by means of some external agent such as a transporter or pore. Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell or group of cells. The process by which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system. The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell. The process by which proteins are secreted into the extracellular milieu via the type I secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins. The controlled release of a substance by a cell. The regulated release of immunoglobulins from a B cell or plasma cell, whose mechanism includes the use of alternate polyadenylylation signals to favor the biosynthesis of secreted forms of immunoglobulin over membrane-bound immunoglobulin.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: protein secretion
Acc: GO:0009306
Aspect: Biological Process
Desc: The controlled release of proteins from a cell or group of cells.
Synonyms:
  • GO:0045166
  • glycoprotein secretion
  • protein secretion resulting in cell fate commitment
  • GO:0045731
  • protein secretion during cell fate commitment
Proteins in PDR annotated with:
   This term: 337 [Search]
   Term or descendants: 611 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0009306 - protein secretion (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle