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Catalysis of the reaction: dTTP + thioredoxin disulfide + H2O = TTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin. Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin. Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin. Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a disulfide group.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: ribonucleoside-triphosphate reductase activity
Acc: GO:0008998
Aspect: Molecular Function
Desc: Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin.
Synonyms:
  • 2'-deoxyribonucleoside-triphosphate:thioredoxin-disulfide 2'-oxidoreductase activity
  • 2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase activity
  • ribonucleotide reductase activity
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008998 - ribonucleoside-triphosphate reductase activity (interactive image map)
YRC Informatics Platform - Version 3.0
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