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The conversion of proteins that induce or sustain apoptosis to an active form. Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. Any process that activates or increases the frequency, rate or extent of cell death by apoptosis. A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell. Any process that modulates the occurrence or rate of cell death by apoptosis. Cell death resulting from activation of endogenous cellular processes.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: activation of pro-apoptotic gene products
Acc: GO:0008633
Aspect: Biological Process
Desc: The conversion of proteins that induce or sustain apoptosis to an active form.
Synonyms:
  • induction of pro-apoptotic gene products
Proteins in PDR annotated with:
   This term: 29 [Search]
   Term or descendants: 29 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008633 - activation of pro-apoptotic gene products (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle