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Any process that modulates the frequency, rate or extent of the transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane. Any process that activates or increases the frequency, rate or extent of transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane. The release of NF-kappaB from specific molecules in the cytoplasm to which it was bound, thereby allowing its translocation into the nucleus. The directed movement of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane. A series of reactions initiated by the activation of the transcription factor NF-kappaB. NF-kappaB is sequestered by the inhibitor I-kappaB, and is released when I-kappaB is phosphorylated by activated I-kappaB kinase. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. A series of reactions that occur within the cell, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: release of cytoplasmic sequestered NF-kappaB
Acc: GO:0008588
Aspect: Biological Process
Desc: The release of NF-kappaB from specific molecules in the cytoplasm to which it was bound, thereby allowing its translocation into the nucleus.
Synonyms:
  • activation of NF-kappa B
  • negative regulation of cytoplasmic NF-kappaB sequestering
  • negative regulation of cytoplasmic NF-kappaB retention
  • negative regulation of cytoplasmic NF-kappaB storage
  • release of NF-kappaB stored in cytoplasm
  • release of NF-kappaB sequestered in cytoplasm
  • negative regulation of cytoplasmic NF-kappaB sequestration
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008588 - release of cytoplasmic sequestered NF-kappaB (interactive image map)
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