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Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule. Catalysis of the hydrolysis of ester linkages within nucleic acids. Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end. Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end. Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule. Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 3'-5' exonuclease activity
Acc: GO:0008408
Aspect: Molecular Function
Desc: Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
Synonyms:
  • 3'-5'-exonuclease activity
Proteins in PDR annotated with:
   This term: 98 [Search]
   Term or descendants: 250 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008408 - 3'-5' exonuclease activity (interactive image map)
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