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Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate. Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein. Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor). Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein. Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor).

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: protein prenyltransferase activity
Acc: GO:0008318
Aspect: Molecular Function
Desc: Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein.
Synonyms:
  • GO:0008244
Proteins in PDR annotated with:
   This term: 13 [Search]
   Term or descendants: 58 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008318 - protein prenyltransferase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle