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The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane. The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups. The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups. The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane. The chemical reactions and pathways resulting in the formation of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane. The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: spermidine biosynthetic process
Acc: GO:0008295
Aspect: Biological Process
Desc: The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
Synonyms:
  • spermidine formation
  • spermidine biosynthesis
  • spermidine anabolism
  • spermidine synthesis
Proteins in PDR annotated with:
   This term: 40 [Search]
   Term or descendants: 40 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008295 - spermidine biosynthetic process (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle