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Stops, prevents or reduces the activity of an enzyme. Modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. Stops, prevents or reduces the activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal. Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity. Modulates the activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal. Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: metalloendopeptidase inhibitor activity
Acc: GO:0008191
Aspect: Molecular Function
Desc: Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity.
Synonyms:
  • metalloprotease inhibitor
  • metalloproteinase inhibitor
Proteins in PDR annotated with:
   This term: 15 [Search]
   Term or descendants: 15 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008191 - metalloendopeptidase inhibitor activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle