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Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins. Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes. The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. The lipid bilayer surrounding a synaptic vesicle. The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together. The volume enclosed by the synaptic vesicle membrane. A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and is secreted these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: synaptic vesicle
Acc: GO:0008021
Aspect: Cellular Component
Desc: A secretory organelle, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and is secreted these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
Proteins in PDR annotated with:
   This term: 306 [Search]
   Term or descendants: 356 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008021 - synaptic vesicle (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle