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The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand. The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by modulation of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP. Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase activity. The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to one of its physiological ligands; muscarinic acetylcholine receptors activate inhibitory G proteins and can be activated by the fungal alkaloid muscarine. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway
Acc: GO:0007197
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
Synonyms:
  • muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway
  • inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signalling pathway
  • muscarinic acetylcholine receptor, adenylyl cyclase inhibiting pathway
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007197 - inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway (interactive image map)
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Created and Maintained by: Michael Riffle