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The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by modulation of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide. A series of molecular signals in which an ion or small molecule is formed or released into the cytosol, thereby helping relay the signal within the cell. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase and a subsequent increase in the concentration of cyclic GMP. The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by modulation of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP. A series of molecular signals in which a cell uses a cyclic nucleotide to convert an extracellular signal into a response. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: G-protein signaling, coupled to cyclic nucleotide second messenger
Acc: GO:0007187
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by modulation of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.
Synonyms:
  • G protein signaling, coupled to cyclic nucleotide second messenger
  • G-protein signalling, coupled to cyclic nucleotide second messenger
  • G protein signalling, coupled to cyclic nucleotide second messenger
Proteins in PDR annotated with:
   This term: 9 [Search]
   Term or descendants: 242 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007187 - G-protein signaling, coupled to cyclic nucleotide second messenger (interactive image map)
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