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The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands. The series of molecular signals generated as a consequence of the nerve growth factor receptor binding to one of its physiological ligands. The series of molecular signals generated as a consequence of the hepatocyte growth factor receptor binding to one of its physiological ligands. The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin. The series of molecular signals generated as a consequence of a Tie receptor binding to one of its physiological ligands (angiopoietins). The series of molecular signals generated as a consequence of the torso transmembrane receptor tyrosine kinase binding to its physiological ligand. The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand. The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands. Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity. The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell. Complex formation involves dimerization of a receptor protein tyrosine kinase followed by the association of several different intracellular signaling molecules with the cytoplasmic tails of the receptors. The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands. The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands. The series of molecular signals generated as a consequence of the sevenless receptor binding to one of its physiological ligands. The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands. The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands. The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: transmembrane receptor protein tyrosine kinase signaling pathway
Acc: GO:0007169
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.
Synonyms:
  • transmembrane receptor protein tyrosine kinase signalling pathway
Proteins in PDR annotated with:
   This term: 363 [Search]
   Term or descendants: 1077 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007169 - transmembrane receptor protein tyrosine kinase signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle