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Any process that stops, prevents or reduces the frequency, rate, or extent of cell adhesion mediated by integrin. Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules. The process that results in the loss of attachments of a cell in the ventricular zone. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion. Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction. The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. The attachment of a cell or organism to a substrate or other organism.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of cell adhesion
Acc: GO:0007162
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion.
Synonyms:
  • cell adhesion receptor inhibitor activity
  • downregulation of cell adhesion
  • inhibition of cell adhesion
  • down regulation of cell adhesion
  • down-regulation of cell adhesion
Proteins in PDR annotated with:
   This term: 38 [Search]
   Term or descendants: 117 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007162 - negative regulation of cell adhesion (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle