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Any process that modulates the frequency, rate or extent of microtubule depolymerization. Any process that activates or increases the frequency, rate or extent of microtubule depolymerization. The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule. The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules. Any process that stops, prevents or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell. The process by which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein. Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule. The removal of tubulin heterodimers from the plus end of a microtubule. The removal of tubulin heterodimers from one or both ends of a microtubule. The disaggregation of a protein complex into its constituent components, occurring at the level of an individual cell. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: microtubule depolymerization
Acc: GO:0007019
Aspect: Biological Process
Desc: The removal of tubulin heterodimers from one or both ends of a microtubule.
Synonyms:
  • microtubule catastrophe
  • microtubule disassembly
  • microtubule depolymerization during nuclear congression
Proteins in PDR annotated with:
   This term: 18 [Search]
   Term or descendants: 113 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007019 - microtubule depolymerization (interactive image map)
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