YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

The process by which cells degrade mature ribosomes under conditions of starvation. The process by which mitochondria are delivered to the vacuole and degraded in response to changing cellular conditions, autophagy of mitochondria. The transfer of cytosolic components into the lysosomal compartment by direct invagination of the lysosomal membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. In S. cerevisiae, the vacuole is the lysosomal compartment. The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane-bounded autophagic bodies which are then degraded within the lysosome (or vacuole). Though once thought to be a purely non-selective process, it appears that some types of macroautophagy, e.g. macropexophagy, macromitophagy, may involve selective targeting of the targets to be degraded. The process by which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. The process by which cells digest parts of their own cytoplasm during a symbiotic interaction; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. The host is defined as the larger of the organisms involved in a symbiotic interaction. The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process by which cells digest parts of their own cytoplasm. Any process that stops, prevents or reduces the frequency, rate or extent of autophagy. Autophagy is the process by which cells digest parts of their own cytoplasm. Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process by which cells digest parts of their own cytoplasm. The process by which cells digest parts of their own cytoplasm in response to the accumulation of misfolded proteins in the endoplasmic reticulum. The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. The process by which peroxisomes are delivered to the vacuole and degraded in response to changing nutrient conditions. null The chemical reactions and pathways by which individual cells transform chemical substances. Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process by which cells digest parts of their own cytoplasm.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: autophagy
Acc: GO:0006914
Aspect: Biological Process
Desc: The process by which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
Proteins in PDR annotated with:
   This term: 192 [Search]
   Term or descendants: 287 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006914 - autophagy (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle