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The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome. The directed movement of substances into, out of or within a vacuole. The process of directing proteins towards the lysosome using signals contained within the protein. The process of directing proteins towards the vacuole, usually using signals contained within the protein. The directed movement of substances into, out of or within a lysosome. The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: protein targeting to lysosome
Acc: GO:0006622
Aspect: Biological Process
Desc: The process of directing proteins towards the lysosome using signals contained within the protein.
Synonyms:
  • protein-lysosome targeting
Proteins in PDR annotated with:
   This term: 17 [Search]
   Term or descendants: 20 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006622 - protein targeting to lysosome (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle