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The chemical reactions and pathways resulting in the formation from tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. The process by which the tryptophan 5-monooxygenase enzyme is changed so that it can carry out its enzymatic activity. The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. Any process that activates or increases the activity of a monooxygenase. Any process that modulates the activity of a monooxygenase. The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: activation of tryptophan 5-monooxygenase activity
Acc: GO:0006588
Aspect: Biological Process
Desc: The process by which the tryptophan 5-monooxygenase enzyme is changed so that it can carry out its enzymatic activity.
Synonyms:
  • tryptophan hydroxylase activation
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006588 - activation of tryptophan 5-monooxygenase activity (interactive image map)
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