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Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. Any process by which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner. Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. Any process that modulates the frequency, rate or extent of mRNA cleavage, any process by which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner. The nucleic acid metabolic process by which the phosphodiester bonds between nucleotides are cleaved by hydrolysis. Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cleavage. Any cellular metabolic process involving nucleic acids. The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. Any process that activates or increases the frequency, rate or extent of mRNA cleavage. The process by which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically direct cleavage by base pairing with near-perfect complementarity to the target mRNA. Many plant miRNAs downregulate gene expression through this mechanism.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: mRNA cleavage
Acc: GO:0006379
Aspect: Biological Process
Desc: Any process by which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
Synonyms:
  • cleavage and polyadenylylation specificity factor activity
  • cleavage stimulation factor activity
  • pre-mRNA cleavage factor activity
Proteins in PDR annotated with:
   This term: 104 [Search]
   Term or descendants: 115 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006379 - mRNA cleavage (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle