YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule that contributes to chromatin silencing. Any epigenetic process that stops, prevents or reduces the rate of gene expression. Repression of transcription by methylation of DNA, leading to the formation of heterochromatin. Any process that modulates the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin. Any process that increases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin. Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. Any process that decreases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin. Any process that stops, prevents or reduces the frequency, rate or extent of cellular DNA-dependent transcription. The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups. The alteration of DNA or protein in chromatin, which may result in changing the chromatin structure.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: methylation-dependent chromatin silencing
Acc: GO:0006346
Aspect: Biological Process
Desc: Repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
Synonyms:
  • methylation-dependent heterochromatic silencing
Proteins in PDR annotated with:
   This term: 12 [Search]
   Term or descendants: 12 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006346 - methylation-dependent chromatin silencing (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle