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The initial formation of a transcriptionally silent chromatin structure such as heterochromatin at the telomere. The initial formation of a transcriptionally silent chromatin structure such as heterochromatin. Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. The initial formation of a transcriptionally silent chromatin structure such as heterochromatin at silent mating-type loci. Any epigenetic process that stops, prevents or reduces the rate of gene expression. Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. Any process that stops, prevents or reduces the frequency, rate or extent of cellular DNA-dependent transcription. The alteration of DNA or protein in chromatin, which may result in changing the chromatin structure.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: establishment of chromatin silencing
Acc: GO:0006343
Aspect: Biological Process
Desc: The initial formation of a transcriptionally silent chromatin structure such as heterochromatin.
Synonyms:
  • establishment of heterochromatic silencing
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006343 - establishment of chromatin silencing (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle