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The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. The repair of UV-induced T-T, C-T and C-C dimers. Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines. A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: pyrimidine dimer repair
Acc: GO:0006290
Aspect: Biological Process
Desc: The repair of UV-induced T-T, C-T and C-C dimers.
Proteins in PDR annotated with:
   This term: 9 [Search]
   Term or descendants: 16 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006290 - pyrimidine dimer repair (interactive image map)
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