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The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. Any cellular metabolic process involving nucleic acids. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule. Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. The process by which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: DNA topological change
Acc: GO:0006265
Aspect: Biological Process
Desc: The process by which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
Synonyms:
  • DNA underwinding
Proteins in PDR annotated with:
   This term: 118 [Search]
   Term or descendants: 118 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006265 - DNA topological change (interactive image map)
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