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The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate. The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-). The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle. The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including succinate. The anaerobic conversion of pyruvate to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate. The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes. The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: succinate metabolic process
Acc: GO:0006105
Aspect: Biological Process
Desc: The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.
Synonyms:
  • succinate metabolism
Proteins in PDR annotated with:
   This term: 23 [Search]
   Term or descendants: 32 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006105 - succinate metabolic process (interactive image map)
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