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A cell junction that forms a connection between a cell and the extracellular matrix. A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments. An adherens junction which connects a cell to the extracellular matrix. Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: focal adhesion
Acc: GO:0005925
Aspect: Cellular Component
Desc: Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
Synonyms:
  • hemi-adherens junction
  • GO:0008357
  • focal contact
Proteins in PDR annotated with:
   This term: 213 [Search]
   Term or descendants: 213 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005925 - focal adhesion (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle