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A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. The lipid bilayer surrounding a multivesicular body. A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: multivesicular body
Acc: GO:0005771
Aspect: Cellular Component
Desc: A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
Synonyms:
  • MVB
  • multivesicular endosome
  • MVE
Proteins in PDR annotated with:
   This term: 58 [Search]
   Term or descendants: 61 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005771 - multivesicular body (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle