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Interacting selectively and non-covalently with a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. Combining with a C-X3-C chemokine to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif. Combining with a C-X-C chemokine to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif. Combining with chemokines, small chemoattractant molecules normally used to stimulate leukocytes, to initiate a change in cell activity. Combining with an extracellular or intracellular peptide to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state. Combining with a C-C chemokine to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif. null Interacting selectively and non-covalently with a chemokine, any of a subgroup of cytokines which act primarily on hemopoietic cells in acute and inflammatory processes and other immunoregulatory functions.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: chemokine receptor activity
Acc: GO:0004950
Aspect: Molecular Function
Desc: Combining with chemokines, small chemoattractant molecules normally used to stimulate leukocytes, to initiate a change in cell activity.
Proteins in PDR annotated with:
   This term: 12 [Search]
   Term or descendants: 49 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004950 - chemokine receptor activity (interactive image map)
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